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Best Route Through Honduras

Short version: I suppose I'm asking for any advice on the best route through Honduras from Guatemala to Nicaragua. Any roads/towns/etc. to avoid? Any to seek out?

Long version: Hello everyone, my girlfriend and I have been overlanding south from Vancouver Island for just over 2 months. We're currently in the Yucatan, planning to cross into Belize in the next few days, and then into Guatemala about a week after that. After spending about two weeks in Guatemala, we want to book it through Hondruas to get to Nicaragua for Xmas.